News

  • Heart Patients Help Doctors Determine Best Aspirin Dose

    Doctors have known for decades that taking aspirin can reduce the risk for future heart attacks and strokes in people with cardiovascular disease. What is less clear is which dose is best. Participants in a new kind of clinical trial are helping them find out. Which Aspirin Dose Is Best? Some doctors prescribe a “baby aspirin” (81mg) ...
  • 2017: Year in Review

    The ADAPTABLE Study team reflects on the many accomplishments and milestones throughout 2017 — a year of record enrollment, new network collaborations, and actively engaging with and sharing the voice of study participants. We wish you the best in 2018 and look forward to continuing to build a community where participants, researchers, and clinicians partner ...
  • ADAPTABLE Study Welcomes HealthCore and LHSNet Networks to the Team

    The National Patient-Centered Clinical Research Network (PCORnet) demonstration study, ADAPTABLE, welcomes two new partners as participating networks: HealthCore-Anthem Research Network and Patient-Centered Network of Learning Health Systems (LHSNet). HealthCore, a subsidiary of Anthem, is a health plan research network with 140 highly specialized, multi-disciplinary professionals dedicated to health services and outcomes research. Through Anthem, HealthCore has ...
  • ADAPTABLE Reaches Enrollment Milestone of 5,000 Participants

    Enrollment for the Aspirin Dosing: A Patient-centric Trial Assessing Benefits and Long-Term Effectiveness (ADAPTABLE) study has reached 5,000 participants. With its coordinating center based at the Duke Clinical Research Institute, the ADAPTABLE study is a large three-year pragmatic trial assessing two different doses of aspirin – 81mg and 325mg – to evaluate which dose is more effective ...
  • Sharing Art and Stories to Honor Clinical Trial Participants

    Hero’s Journey Art Piece ADAPTABLE patient partners participated in the Hero’s Journey art project. Sponsored by Eli Lilly, the national art project involves more than 1,000 participants and is intended to honor clinical trial participants and raise awareness of clinical trials. In conjunction with Health eHeart Alliance, ADAPTABLE’s patient partners crafted the quote “Better health outcomes for all when patients ...
  • Engagement, Research, and Evidence

    ADAPTABLE is leading the way in patient-researcher partnerships.  A recent example of this collaboration is an insightful perspective piece for Circulation authored by Adrian Hernandez, ADAPTABLE Study Co-PI, and Henry Cruz, a patient Adaptor. Hernandez and Cruz discuss the need for and benefits of a national learning health system and how PCORnet, The National Patient-Centered Research Network is ...
  • ADAPTABLE Study: Patient-Researcher Partnerships Produce Better Outcomes

    Amidst large vendor booths showcasing the latest advances in cardiovascular innovation at the 66th Annual American College of Cardiology Scientific Session and Expo, Henry Cruz and Tom McCormick, patient partners on the ADAPTABLE Study team, answered questions at the CardioSmart Patient Engagement Pavilion and later participated in a panel discussion on leveraging patient engagement to ...
  • NEJM Highlights How the ADAPTABLE Study is Changing Clinical Research

    ADAPTABLE’s electronic consent processes and web-based design are featured in a multi-part review article by the New England Journal of Medicine on The Changing Face of Clinical Trials. New approaches to informed consent and innovative options for obtaining it have come about from technological advances and pragmatic research designs. While answering the question of what is ...
  • ADAPTABLE Advances Groundbreaking Patient Engagement Model

    February is ADAPTABLE’s time to shine. The groundbreaking pragmatic clinical trial coordinated by the Duke Clinical Research Institute, ADAPTABLE is comparing the effectiveness of two different daily doses of aspirin widely used to prevent heart attacks and strokes in individuals living with heart disease. The study is funded through a PCORI grant and is the first ...
  • An Aspirin a Day—But What’s the Best Dose?

    In a new PCORI blog post recognizing American Heart Month, research partners Adrian Hernandez and Henry Cruz describe the progress and strengths of the ADAPTABLE Study. ADAPTABLE aims to improve the health of people with heart disease, but also to show what’s possible when you have an engaged community using a resource such as PCORnet ...